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Fair is Foul

Source Blood of the Coven pg. 21
School transmutation [curse]; Level antipaladin 2, arcanist 4, cleric/oracle 3, shaman 3, sorcerer/wizard 4, spiritualist 3, warpriest 3, witch 2

Casting

Casting Time 1 standard action
Components V, S, M (a newt eye)

Effect

Range touch
Target creature touched
Duration permanent (D)
Saving Throw Fort negates; Spell Resistance yes

Description

You curse the target with a disfiguring or painful mutation. The target gains one random deformity from the Arcane Malignancies table (see page 10). The curse bestowed by this spell cannot be dispelled but can be removed with a break enchantment, limited wish, miracle, remove curse, or wish spell.